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Home » Evidences » Interventions with Positive Financial Outcomes » Cost-effectiveness of a pragmatic structured education intervention for the prevention of type 2 diabetes: economic evaluation of data from the Let’s Prevent Diabetes cluster-randomised controlled trial.

Cost-effectiveness of a pragmatic structured education intervention for the prevention of type 2 diabetes: economic evaluation of data from the Let’s Prevent Diabetes cluster-randomised controlled trial.

Submitted by admin on Tue, 08/21/2018 - 17:39

Author(s):

Leal, J., et al.

Year Published:

2017

Journal:

BMJ Open

Categories:

Interventions with Positive Financial Outcomes , Diabetes

Link to Abstract Summary:

https://www.ncbi.nlm.nih.gov/pubmed/28069625

Link to Full Article Free Online:

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5223732/

Abstract:

OBJECTIVES: Prevention of type 2 diabetes mellitus (TD2M) is a priority for healthcare systems. We estimated the cost-effectiveness compared with standard care of a structured education programme (Let's Prevent) targeting lifestyle and behaviour change to prevent progression to T2DM in people with prediabetes. DESIGN: Cost-effectiveness analysis alongside randomised controlled trial. SETTING: 44 general practices in Leicestershire, England. PARTICIPANTS: 880 participants with prediabetes randomised to receive either standard care or a 6-hour group structured education programme with follow-up sessions in a primary care setting. MAIN OUTCOME MEASURE: Incremental cost utility from the UK National Health Service (NHS) perspective. Quality of life and resource use measured from baseline and during the 36 months follow-up using the EuroQoL EQ-5D and 15D instruments and an economic questionnaire. Outcomes measured using quality-adjusted life years (QALYs) and healthcare costs calculated in 2012-2013 prices. RESULTS: After accounting for clustering and missing data, the intervention group was found to have a net gain of 0.046 (95% CI -0.0171 to 0.109) QALYs over 3 years, adjusted for baseline utility, at an additional cost of pound168 (95% CI -395 to 732) per patient compared with the standard care group. The incremental cost-effectiveness ratio is pound3643/QALY with an 86% probability of being cost-effective at a willingness to pay threshold of pound20 000/QALY. CONCLUSIONS: The education programme had higher costs and higher quality of life compared with the standard care group. The Let's Prevent programme is very likely to be cost-effective at a willingness to pay threshold of pound20 000/QALY gained. TRIAL REGISTRATION NUMBER: ISRCTN80605705.

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